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TOLLIP 抗体 (AA 86-163)

This anti-TOLLIP antibody is a 兔 多克隆 antibody detecting TOLLIP in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7172257
发货至: 中国

Quick Overview for TOLLIP 抗体 (AA 86-163) (ABIN7172257)

抗原

See all TOLLIP 抗体
TOLLIP (Toll Interacting Protein (TOLLIP))

适用

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宿主

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克隆类型

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多克隆

标记

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This TOLLIP antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 86-163

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Toll-interacting protein (86-163AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    TOLLIP (Toll Interacting Protein (TOLLIP))

    别名

    TOLLIP

    背景

    Background: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).

    Aliases: Adapter protein antibody, FLJ33531 antibody, IL 1RAcPIP antibody, IL1RAcPIP antibody, TOLIP antibody, TOLIP_HUMAN antibody, Toll interacting protein antibody, Toll-interacting protein antibody, tollip antibody

    UniProt

    Q9H0E2
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