TBC1D7 抗体 (AA 1-293)
Quick Overview for TBC1D7 抗体 (AA 1-293) (ABIN7171658)
抗原
See all TBC1D7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-293
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human TBC1 domain family member 7 protein (1-293AA)
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亚型
- IgG
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anti-TBC1 Domain Family, Member 7 (TBC1D7) (AA 1-293) antibody
TBC1D7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 7 (TBC1D7) (AA 154-203) antibodyTBC1D7 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 7 (TBC1D7) antibodyTBC1D7 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))
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别名
- TBC1D7
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背景
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Background: Component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.
Aliases: TBC1D7 antibody, TBC7 antibody, HSPC239 antibody, TBC1 domain family member 7 antibody, Cell migration-inducing protein 23 antibody
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UniProt
- Q9P0N9
抗原
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