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LY9 抗体 (AA 160-360)

This anti-LY9 antibody is a 兔 多克隆 antibody detecting LY9 in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7171457
发货至: 中国

Quick Overview for LY9 抗体 (AA 160-360) (ABIN7171457)

抗原

See all LY9 (CD229) 抗体
LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

适用

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宿主

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克隆类型

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多克隆

标记

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This LY9 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 160-360

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human T-lymphocyte surface antigen Ly-9 protein (160-360AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

    别名

    LY9

    背景

    Background: Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction. Promotes T-cell differentiation into a helper T-cell Th17 phenotype leading to increased IL-17 secretion, the costimulatory activity requires SH2D1A (PubMed:22184727). Promotes recruitment of RORC to the IL-17 promoter (PubMed:22989874). May be involved in the maintenance of peripheral cell tolerance by serving as a negative regulator of the immune response. May disable autoantibody responses and inhibit IFN-gamma secretion by CD4(+) T-cells. May negatively regulate the size of thymic innate CD8(+) T-cells and the development of invariant natural killer T (iNKT) cells (By similarity).

    Aliases: CD229 antibody, Cell surface molecule Ly-9 antibody, Cell surface molecule Ly9 antibody, hly9 antibody, LY 9 antibody, Ly9 antibody, LY9_HUMAN antibody, Lymphocyte antigen 9 antibody, mLY9 antibody, Signaling lymphocytic activation molecule 3 antibody, SLAM family member 3 antibody, SLAMF3 antibody, T lymphocyte surface antigen Ly9 precursor antibody, T-lymphocyte surface antigen Ly-9 antibody

    UniProt

    Q9HBG7

    途径

    BCR Signaling
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