SOCS7 抗体 (AA 6-165)
Quick Overview for SOCS7 抗体 (AA 6-165) (ABIN7171009)
抗原
See all SOCS7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-165
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交叉反应
- 人, 大鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Suppressor of cytokine signaling 7 protein (6-165AA)
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亚型
- IgG
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anti-Suppressor of Cytokine Signaling 7 (SOCS7) (Internal Region) antibody
Verified SOCS7 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 7 (SOCS7) (AA 35-84) antibodySOCS7 适用: 人, 小鼠, 大鼠, Cow, 兔, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 7 (SOCS7) (N-Term) antibodySOCS7 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 7 (SOCS7) (AA 458-486) antibodySOCS7 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
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别名
- SOCS7
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背景
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Background: Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Aliases: Ash and phospholipase C gamma-binding protein antibody, NAP 4 antibody, NAP 4 Fragment antibody, NAP-4 antibody, NAP4 antibody, Nck antibody, Nck Ash and phospholipase C binding protein antibody, Nck Ash and phospholipase C gamma binding protein antibody, Nck associated protein 4 antibody, Nck-associated protein 4 antibody, NCKAP4 antibody, SH2 domain containing SOCS box protein antibody, SOCS 7 antibody, SOCS-7 antibody, SOCS4 antibody, SOCS6 antibody, Socs7 antibody, SOCS7_HUMAN antibody, Suppressor of cytokine signaling 7 antibody
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UniProt
- O14512
抗原
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