SOCS4 抗体 (AA 1-270)
Quick Overview for SOCS4 抗体 (AA 1-270) (ABIN7171004)
抗原
See all SOCS4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-270
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交叉反应
- 人, 小鼠
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Suppressor of cytokine signaling 4 protein (1-270AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))
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别名
- SOCS4
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背景
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Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.
Aliases: CIS4 antibody, Cish4 antibody, Cytokine inducible SH2 protein 4 antibody, DKFZp686J1568 antibody, HSPC060 antibody, SH2 domain containing SOCS box protein antibody, SOCS-4 antibody, SOCS-7 antibody, SOCS4 antibody, SOCS4_HUMAN antibody, SOCS6 antibody, SOCS7 antibody, SSI4 antibody, STAI4 antibody, STAT induced STAT inhibitor 4 antibody, STAT4 antibody, STATI4 antibody, Suppressor of cytokine signaling 4 antibody, Suppressor of cytokine signaling 7 antibody
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UniProt
- Q8WXH5
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途径
- JAK/STAT Signaling, EGFR Signaling Pathway
抗原
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