SUN2 抗体 (AA 45-155)
Quick Overview for SUN2 抗体 (AA 45-155) (ABIN7170975)
抗原
See all SUN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 45-155
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human SUN domain-containing protein 2 protein (45-155AA)
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亚型
- IgG
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anti-Sad1 and UNC84 Domain Containing 2 (SUN2) antibody
SUN2 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) antibodySUN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) (Internal Region) antibodySUN2 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) (AA 75-124) antibodySUN2 适用: 人, 大鼠, 小鼠, Cow, 犬, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) (AA 254-303) antibodySUN2 适用: 人, 大鼠, 兔, 马, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) (AA 326-375) antibodySUN2 适用: 人, 大鼠, 小鼠, 兔, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) antibodySUN2 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) antibodySUN2 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))
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别名
- SUN2
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背景
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Background: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Specifically, SYNE2 and SUN2 assemble in arrays of transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow during actin-dependent nuclear movement. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Required for nuclear migration in retinal photoreceptor progenitors implicating association with cytoplasmic dynein-dynactin and kinesin motor complexes, and probably B-type lamins, SUN1 and SUN2 seem to act redundantly. The SUN1/2:KASH5 LINC complex couples telomeres to microtubules during meiosis, SUN1 and SUN2 seem to act at least partial redundantly. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. May also function on endocytic vesicles as a receptor for RAB5-GDP and participate in the activation of RAB5.
Aliases: SUN2 antibody, FRIGG antibody, KIAA0668 antibody, RAB5IP antibody, UNC84B antibody, SUN domain-containing protein 2 antibody, Protein unc-84 homolog B antibody, Rab5-interacting protein antibody, Rab5IP antibody, Sad1/unc-84 protein-like 2 antibody
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UniProt
- Q9UH99
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途径
- Maintenance of Protein Location, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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