Stim2 抗体 (AA 471-656) (Biotin)
Quick Overview for Stim2 抗体 (AA 471-656) (Biotin) (ABIN7170838)
抗原
See all Stim2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 471-656
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Stromal interaction molecule 2 protein (471-656AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Stim2 (Stromal Interaction Molecule 2 (Stim2))
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别名
- STIM2
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背景
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Background: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx.
Aliases: FLJ39527 antibody, KIAA1482 antibody, STIM 2 antibody, STIM2 antibody, STIM2_HUMAN antibody, Stromal interaction molecule 2 antibody
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UniProt
- Q9P246
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途径
- TCR Signaling, BCR Signaling
抗原
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