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STIM1 抗体 (AA 2-350) (FITC)

This anti-STIM1 antibody is a 兔 多克隆 antibody detecting STIM1 in not_set. Suitable for 人.
产品编号 ABIN7170835
发货至: 中国
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Quick Overview for STIM1 抗体 (AA 2-350) (FITC) (ABIN7170835)

抗原

See all STIM1 抗体
STIM1 (Stromal Interaction Molecule 1 (STIM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This STIM1 antibody is conjugated to FITC

应用范围

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  • 抗原表位

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    AA 2-350

    原理

    STIM1 Antibody, FITC conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Stromal interaction molecule 1 protein (2-350AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    STIM1 (Stromal Interaction Molecule 1 (STIM1))

    别名

    STIM1

    背景

    Background: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores (PubMed:15866891, PubMed:16005298, PubMed:16208375, PubMed:16537481, PubMed:16733527, PubMed:16766533, PubMed:16807233, PubMed:18854159, PubMed:19249086, PubMed:22464749, PubMed:24069340, PubMed:24351972, PubMed:24591628, PubMed:26322679, PubMed:25326555). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1 (PubMed:16208375, PubMed:16537481). Involved in enamel formation (PubMed:24621671). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch (PubMed:26322679).

    Aliases: D11S4896E antibody, GOK antibody, OTTHUMP00000164512 antibody, OTTHUMP00000229140 antibody, OTTHUMP00000230742 antibody, SIM antibody, STIM 1 antibody, STIM1 antibody, Stim1 stromal interaction molecule 1 antibody, STIM1_HUMAN antibody, STIM1L antibody, Stromal interaction molecule 1 antibody

    UniProt

    Q13586

    途径

    TCR Signaling, BCR Signaling
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