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STAMBP 抗体 (AA 1-424)

This anti-STAMBP antibody is a 兔 多克隆 antibody detecting STAMBP in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7170686
发货至: 中国

Quick Overview for STAMBP 抗体 (AA 1-424) (ABIN7170686)

抗原

See all STAMBP 抗体
STAMBP (STAM Binding Protein (STAMBP))

适用

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宿主

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克隆类型

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多克隆

标记

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This STAMBP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-424

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human STAM-binding protein (1-424AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    STAMBP (STAM Binding Protein (STAMBP))

    别名

    STAMBP

    背景

    Background: Zinc metalloprotease that specifically cleaves \\\'Lys-63\\\'-linked polyubiquitin chains. Does not cleave \\\'Lys-48\\\'-linked polyubiquitin chains.Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization .Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.

    Aliases: AMSH antibody, Associated molecule with the SH3 domain of STAM antibody, Endosome associated ubiquitin isopeptidase antibody, Endosome-associated ubiquitin isopeptidase antibody, MGC126516 antibody, MGC126518 antibody, MICCAP antibody, STABP_HUMAN antibody, STAM binding protein antibody, STAM-binding protein antibody, Stambp antibody

    UniProt

    O95630
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