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Sortilin 1 抗体 (AA 328-457) (FITC)

This anti-Sortilin 1 antibody is a 兔 多克隆 antibody detecting Sortilin 1 in . Suitable for 人.
产品编号 ABIN7170337
发货至: 中国

Quick Overview for Sortilin 1 抗体 (AA 328-457) (FITC) (ABIN7170337)

抗原

See all Sortilin 1 (SORT1) 抗体
Sortilin 1 (SORT1)

适用

  • 51
  • 36
  • 30
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 50
  • 7
  • 2

克隆类型

  • 50
  • 9
多克隆

标记

  • 30
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Sortilin 1 antibody is conjugated to FITC

应用范围

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  • 抗原表位

    • 16
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 328-457

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Sortilin protein (328-457AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Sortilin 1 (SORT1)

    别名

    SORT1

    背景

    Background: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.

    Aliases: 100 kDa NT receptor antibody, Glycoprotein 95 antibody, Gp 95 antibody, Gp95 antibody, LDLCQ6 antibody, Neurotensin receptor 3 antibody, NT 3 antibody, NT3 antibody, NTR 3 antibody, NTR3 antibody, OTTHUMP00000013784 antibody, SORT 1 antibody, SORT_HUMAN antibody, SORT1 (gene name) antibody, Sort1 antibody, Sortilin 1 antibody, Sortilin antibody

    UniProt

    Q99523

    途径

    Neurotrophin Signaling Pathway
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