SPPL2B 抗体 (AA 492-592) (HRP)
Quick Overview for SPPL2B 抗体 (AA 492-592) (HRP) (ABIN7169630)
抗原
See all SPPL2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 492-592
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Signal peptide peptidase-like 2B protein (492-592AA)
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亚型
- IgG
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anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (N-Term) antibody
SPPL2B 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (N-Term) antibodySPPL2B 适用: 人, 大鼠, Cow, 马, 小鼠, Pig, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 93-142) antibodySPPL2B 适用: 人, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 492-592) antibodySPPL2B 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 196-229) antibodySPPL2B 适用: 人 WB 宿主: 兔 Polyclonal RB53139 unconjugated
anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 126-160) antibodySPPL2B 适用: 人 WB 宿主: 兔 Polyclonal RB53138 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))
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别名
- SPPL2B
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背景
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Background: Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing (PubMed:16829952, PubMed:16829951, PubMed:17965014, PubMed:19114711, PubMed:22194595). Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus (PubMed:16829952, PubMed:16829951). May play a role in the regulation of innate and adaptive immunity (PubMed:16829952). Catalyzes the intramembrane cleavage of the simian foamy virus processed leader peptide gp18 of the envelope glycoprotein gp130 dependently of prior ectodomain shedding by furin or furin-like proprotein convertase (PC)-mediated cleavage proteolysis (PubMed:23132852).
Aliases: SPPL2B antibody, IMP4 antibody, KIAA1532 antibody, PSL1 antibody, Signal peptide peptidase-like 2B antibody, SPP-like 2B antibody, SPPL2b antibody, EC 3.4.23.- antibody, Intramembrane protease 4 antibody, IMP-4 antibody, Presenilin homologous protein 4 antibody, PSH4 antibody, Presenilin-like protein 1 antibody
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UniProt
- Q8TCT7
抗原
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