SPPL2B 抗体
(Signal Peptide Peptidase-Like 2B (SPPL2B))
This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| SPPL2B 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| SPPL2B 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| SPPL2B 抗体 (AA 93-142) | 人, Cow | 兔 Polyclonal |
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| SPPL2B 抗体 | 人, 小鼠 | 小鼠 Monoclonal |
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| SPPL2B 抗体 (N-Term) | 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 豚鼠 | 兔 Polyclonal |
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| SPPL2B 抗体 (AA 196-229) | 人 | 兔 Polyclonal |
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| SPPL2B 抗体 (AA 126-160) | 人 | 兔 Polyclonal |
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| SPPL2B 抗体 (AA 492-592) | 人 | 兔 Polyclonal |
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| SPPL2B 抗体 (AA 55-135) | 人 | 兔 Polyclonal |
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| SPPL2B 抗体 (AA 53-102) | 人 | 兔 Polyclonal |
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| SPPL2B 抗体 (AA 492-592) (HRP) | 人 | 兔 Polyclonal |
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| SPPL2B 抗体 (AA 492-592) (Biotin) | 人 | 兔 Polyclonal |
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| SPPL2B 抗体 (AA 492-592) (FITC) | 人 | 兔 Polyclonal |
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| SPPL2B 抗体 | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 有验证图片)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AFfirm8795
- 标记
- unconjugated
- 抗体亚型
- IgG1
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
1 reference - 适用
- 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 豚鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB53139
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 196-229
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB53138
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 126-160
Primary Antibody
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 492-592
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 55-135
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 53-102
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 492-592
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 492-592
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 492-592
Latest Publications for our SPPL2B 抗体
: "BRI2-BRICHOS is increased in human amyloid plaques in early stages of Alzheimer's disease." in: Neurobiology of aging, Vol. 35, Issue 7, pp. 1596-604, (2014) (PubMed).
: "Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins." in: The Journal of biological chemistry, Vol. 279, Issue 49, pp. 50790-8, (2004) (PubMed).
: "Novel class of polytopic proteins with domains associated with putative protease activity." in: Biochemistry. Biokhimii?a, Vol. 67, Issue 7, pp. 826-35, (2002) (PubMed).
: "Identification of signal peptide peptidase, a presenilin-type aspartic protease." in: Science (New York, N.Y.), Vol. 296, Issue 5576, pp. 2215-8, (2002) (PubMed).
: "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 7, Issue 2, pp. 143-50, (2000) (PubMed).
: "Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins." in: The Journal of biological chemistry, Vol. 279, Issue 49, pp. 50790-8, (2004) (PubMed).
: "Novel class of polytopic proteins with domains associated with putative protease activity." in: Biochemistry. Biokhimii?a, Vol. 67, Issue 7, pp. 826-35, (2002) (PubMed).
: "Identification of signal peptide peptidase, a presenilin-type aspartic protease." in: Science (New York, N.Y.), Vol. 296, Issue 5576, pp. 2215-8, (2002) (PubMed).
: "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 7, Issue 2, pp. 143-50, (2000) (PubMed).
Aliases for SPPL2B 抗体
signal peptide peptidase-like 2 (sppl2) 抗体signal peptide peptidase like 2B (sppl2b) 抗体
signal peptide peptidase like 2B S homeolog (sppl2b.S) 抗体
signal peptide peptidase like 2B (SPPL2B) 抗体
signal peptide peptidase like 2B (Sppl2b) 抗体
signal peptide peptidase-like 2B (Sppl2b) 抗体
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