ULK1 抗体 (AA 602-715)
Quick Overview for ULK1 抗体 (AA 602-715) (ABIN7169205)
抗原
See all ULK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 602-715
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Serine/threonine-protein kinase ULK1 protein (602-715AA)
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亚型
- IgG
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anti-Unc-51 Like Kinase 1 (ULK1) (AA 951-1050) antibody
ULK1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (AA 602-715) antibodyULK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (AA 400-499) antibodyULK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) antibodyULK1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (pSer556) antibodyULK1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibodyULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (HRP)ULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal HRP
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (FITC)ULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (Biotin)ULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (PE)ULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PE
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应用备注
- Recommended dilution: IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ULK1 (Unc-51 Like Kinase 1 (ULK1))
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别名
- ULK1
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背景
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Background: Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR, however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation. May also phosphorylate SESN2 and SQSTM1 to regulate autophagy (PubMed:25040165).
Aliases: ATG 1 antibody, ATG1 antibody, ATG1 autophagy related 1 homolog antibody, ATG1A antibody, Autophagy related protein 1 homolog antibody, Autophagy-related protein 1 homolog antibody, FLJ38455 antibody, FLJ46475 antibody, hATG1 antibody, KIAA0722 antibody, Serine/threonine protein kinase ULK1 antibody, Serine/threonine protein kinase Unc51.1 antibody, Serine/threonine-protein kinase ULK1 antibody, ULK 1 antibody, ULK1 antibody, ULK1_HUMAN antibody, Unc 51 (C. elegans) like kinase 1 antibody, UNC 51 antibody, Unc 51 like kinase 1 antibody, Unc-51 like kinase 1 (C. elegans) antibody, Unc-51-like kinase 1 antibody, UNC51 antibody, UNC51, C. elegans, homolog of antibody, Unc51.1 antibody
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UniProt
- O75385
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途径
- Regulation of Cell Size, Autophagy
抗原
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