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Seryl-tRNA Synthetase (SARS) (AA 2-233) 抗体 (HRP)

This HRP-conjugated 兔 多克隆 anti-not_set antibody specifically detects not_set in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7168952
发货至: 中国
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Quick Overview for Seryl-tRNA Synthetase (SARS) (AA 2-233) 抗体 (HRP) (ABIN7168952)

抗原

See all Seryl-tRNA Synthetase (SARS) 抗体
Seryl-tRNA Synthetase (SARS)

适用

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宿主

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克隆类型

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多克隆

标记

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HRP

应用范围

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ELISA
  • 抗原表位

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    AA 2-233

    原理

    SARS Antibody, HRP conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Serine--tRNA ligase, cytoplasmic protein (2-233AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Seryl-tRNA Synthetase (SARS)

    别名

    SARS

    背景

    Background: Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser) (PubMed:22353712, PubMed:24095058, PubMed:9431993, PubMed:26433229, PubMed:28236339). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (PubMed:9431993, PubMed:26433229, PubMed:28236339). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC (PubMed:24940000). Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at \\\'Lys-16\\\' (H4K16). Thereby, inhibits the production of VEGFA and sprouting angiogenesis mediated by VEGFA (PubMed:19423848, PubMed:19423847, PubMed:24940000).

    Aliases: C78314 antibody, cytoplasmic antibody, EC 6.1.1.11 antibody, FLJ36399 antibody, sarS antibody, Sars1 antibody, Serine tRNA ligase 1, cytoplasmic antibody, Serine tRNA ligase antibody, Serine--tRNA ligase antibody, serine--tRNA ligase, cytoplasmic antibody, SerRS antibody, SERS antibody, Seryl tRNA Ser/Sec synthetase antibody, Seryl tRNA synthetase antibody, Seryl tRNA synthetase cytoplasmic antibody, Seryl-tRNA Ser/Sec synthetase antibody, Seryl-tRNA synthetase antibody, seryl-tRNA synthetase, cytoplasmic antibody, Seryl-tRNA(Ser/Sec) synthetase antibody, Strs antibody, SYSC_HUMAN antibody

    UniProt

    P49591
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