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CD163 抗体 (AA 801-940) (Biotin)

This anti-CD163 antibody is a 兔 多克隆 antibody detecting CD163 in ELISA. Suitable for 人.
产品编号 ABIN7168619
发货至: 中国

Quick Overview for CD163 抗体 (AA 801-940) (Biotin) (ABIN7168619)

抗原

See all CD163 抗体
CD163

适用

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宿主

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克隆类型

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多克隆

标记

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This CD163 antibody is conjugated to Biotin

应用范围

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ELISA
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    AA 801-940

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Scavenger receptor cysteine-rich type 1 protein M130 protein (801-940AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CD163

    别名

    CD163

    背景

    Background: Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells.

    Aliases: C163A_HUMAN antibody, CD 163 antibody, CD163 antibody, CD163 antigen antibody, CD163 Molecule antibody, Hemoglobin scavenger receptor antibody, M130 antibody, M130 antigen precursor antibody, Macrophage associated antigen antibody, MM130 antibody, OTTHUMP00000238617 antibody, OTTHUMP00000238618 antibody, OTTHUMP00000238619 antibody, OTTHUMP00000238620 antibody, SCARI1 antibody, Scavenger receptor cysteine rich type 1 protein M130 antibody, sCD163 antibody, Soluble CD163 antibody

    UniProt

    Q86VB7
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