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Rubicon 抗体 (AA 518-733)

This 兔 多克隆 anti-Rubicon antibody specifically detects Rubicon in IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7168473
发货至: 中国
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Quick Overview for Rubicon 抗体 (AA 518-733) (ABIN7168473)

抗原

See all Rubicon (KIAA0226) 抗体
Rubicon (KIAA0226) (KIAA0226)

适用

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宿主

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克隆类型

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多克隆

标记

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This Rubicon antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
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    AA 518-733

    原理

    RUBCN Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (518-733AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Rubicon (KIAA0226) (KIAA0226)

    别名

    RUBCN

    背景

    Background: Inhibits PIK3C3 activity, under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation (PubMed:20974968, PubMed:21062745).

    Aliases: Baron antibody, Beclin 1 associated RUN domain containing protein antibody, Beclin-1 associated RUN domain containing protein antibody, hypothetical protein LOC9711 antibody, Kiaa0226 antibody, OTTHUMP00000208021 antibody, OTTHUMP00000208023 antibody, OTTHUMP00000208024 antibody, RUBIC_HUMAN antibody, Rubicon antibody, RUN domain and cysteine rich domain containing, Beclin 1 interacting protein antibody, Run domain Beclin 1 interacting and cystein rich containing protein antibody, Run domain Beclin-1 interacting and cysteine-rich containing protein antibody, RUN domain protein as Beclin 1 interacting and cysteine rich containing antibody

    UniProt

    Q92622

    途径

    Autophagy
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