RRM1 抗体
Quick Overview for RRM1 抗体 (ABIN7168449)
抗原
See all RRM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Protein G purified
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免疫原
- Recombinant Human RRM1 Protein
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亚型
- IgG
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应用备注
- Recommended dilution:IHC:1:50-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RRM1 (Ribonucleotide Reductase M1 (RRM1))
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别名
- RRM1
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背景
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Background: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells.It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor,rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.
Aliases: Ribonucleotide Reductase M1,RRM1,RR1
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UniProt
- P23921
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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