MOV10L1 抗体 (AA 336-425)
Quick Overview for MOV10L1 抗体 (AA 336-425) (ABIN7168291)
抗原
See all MOV10L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 336-425
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原理
- MOV10L1 Antibody
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human RNA helicase Mov10l1 protein (336-425AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MOV10L1 (Mov10l1, Moloney Leukemia Virus 10-Like 1 (MOV10L1))
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别名
- MOV10L1
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背景
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Background: ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5\\\'-3\\\' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins.
Aliases: Cardiac helicase activated by MEF2 protein antibody, Cardiac specific RNA helicase antibody, CHAMP antibody, Csm antibody, M10L1_HUMAN antibody, Moloney leukemia virus 10 like protein 1 antibody, Moloney leukemia virus 10-like protein 1 antibody, MOV10 like 1 antibody, MOV10 like protein 1 antibody, MOV10-like protein 1 antibody, MOV10L1 antibody, Mov10l1, Moloney leukemia virus 10 like 1, homolog (mouse) antibody, Putative helicase Mov10l1 antibody
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UniProt
- Q9BXT6
抗原
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