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MOV10L1 抗体 (Internal Region)

MOV10L1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259308
发货至: 中国
  • 抗原 See all MOV10L1 抗体
    MOV10L1 (Mov10l1, Moloney Leukemia Virus 10-Like 1 (MOV10L1))
    抗原表位
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 6
    克隆类型
    • 6
    多克隆
    标记
    • 6
    This MOV10L1 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    MOV10L1 Antibody detects endogenous levels of total MOV10L1.
    预测反应
    Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human MOV10L1, corresponding to a region within the internal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    MOV10L1 (Mov10l1, Moloney Leukemia Virus 10-Like 1 (MOV10L1))
    别名
    MOV10L1 (MOV10L1 产品)
    别名
    CHAMP antibody, Csm antibody, DJ402G11.8 antibody, Mov10 RISC complex RNA helicase like 1 antibody, Moloney leukemia virus 10-like 1 antibody, MOV10L1 antibody, mov10l1 antibody, Mov10l1 antibody
    背景

    Description: ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5'-3' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins.

    Gene: MOV10L1

    分子量
    140 kDa
    基因ID
    54456
    UniProt
    Q9BXT6
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