RRM2B 抗体 (AA 1-351)
Quick Overview for RRM2B 抗体 (AA 1-351) (ABIN7168147)
抗原
See all RRM2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-351
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Ribonucleoside-diphosphate reductase subunit M2 B protein (1-351AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
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别名
- RRM2B
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背景
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Background: Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.
Aliases: DKFZp686M05248 antibody, MGC102856 antibody, MGC42116 antibody, MTDPS8A antibody, MTDPS8B antibody, p53 inducible ribonucleotide reductase small subunit 2 homolog antibody, p53 inducible ribonucleotide reductase small subunit 2 like protein antibody, P53 inducible ribonucleotide reductase small subunit 2 short form beta antibody, p53 R2 antibody, p53-inducible ribonucleotide reductase small subunit 2-like protein antibody, p53R2 antibody, Ribonucleoside diphosphate reductase M2 subunit B antibody, Ribonucleoside-diphosphate reductase subunit M2 B antibody, Ribonucleotide reductase M2 B (TP53 inducible) antibody, Ribonucleotide reductase M2 B antibody, Ribonucleotide reductase small subunit like 2 p53 inducible antibody, RIR2B_HUMAN antibody, RRM 2B antibody, RRM2B antibody, TP53 inducible ribonucleotide reductase M2 B antibody, TP53-inducible ribonucleotide reductase M2 B antibody
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UniProt
- Q7LG56
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途径
- p53 Pathway, Negative Regulation of intrinsic apoptotic Signaling
抗原
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