CoREST 抗体 (AA 394-482) (Biotin)
Quick Overview for CoREST 抗体 (AA 394-482) (Biotin) (ABIN7167722)
抗原
See all CoREST (RCOR1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 394-482
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human REST corepressor 1 protein (394-482AA)
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亚型
- IgG
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anti-REST Corepressor 1 (RCOR1) antibody
RCOR1 适用: 人 WB, IHC, IP, ChIP 宿主: 兔 Monoclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (AA 256-485) antibodyRCOR1 适用: 人 WB, IF, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (N-Term) antibodyRCOR1 适用: 人, 小鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (AA 394-482) antibodyRCOR1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (N-Term) antibodyRCOR1 适用: 人, 小鼠, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (AA 109-293) antibodyRCOR1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (C-Term) antibodyRCOR1 适用: 人, 小鼠, 犬, 豚鼠, Cow, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) antibodyRCOR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (C-Term) antibodyRCOR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (AA 101-130), (N-Term) antibodyRCOR1 适用: 人 WB 宿主: 兔 Polyclonal RB36780 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CoREST (RCOR1) (REST Corepressor 1 (RCOR1))
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别名
- RCOR1
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背景
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Background: Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation.
Aliases: COREST antibody, KIAA0071 antibody, Nr2b2 antibody, Nuclear receptor coregulator 1 antibody, Nuclear receptor subfamily 2 group B member 2 antibody, Protein CoREST antibody, RCOR antibody, Rcor1 antibody, RCOR1_HUMAN antibody, REST corepressor 1 antibody, Retinoic acid receptor RXR-beta antibody, Retinoid X receptor beta antibody, Rxrb antibody
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UniProt
- Q9UKL0
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途径
- Regulation of Hormone Metabolic Process, Chromatin Binding
抗原
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