RGS14 抗体 (AA 230-510)
Quick Overview for RGS14 抗体 (AA 230-510) (ABIN7167591)
抗原
See all RGS14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 230-510
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Regulator of G-protein signaling 14 protein (230-510AA)
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亚型
- IgG
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anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 1-566) antibody
RGS14 适用: 人 ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2F8 unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (Internal Region) antibodyRGS14 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (C-Term) antibodyRGS14 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 230-510) antibodyRGS14 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (C-Term) antibodyVerified RGS14 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 1-566) antibodyRGS14 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 201-250) antibodyRGS14 适用: 人, 小鼠, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (C-Term) antibodyRGS14 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 504-516) antibodyRGS14 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:1000-1:5000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
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别名
- RGS14
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背景
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Background: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Besides, modulates signal transduction via G protein alpha subunits by functioning as a GDP-dissociation inhibitor (GDI). Has GDI activity on G(i) alpha subunits GNAI1 and GNAI3, but not on GNAI2 and G(o) alpha subunit GNAO1. Has GAP activity on GNAI0, GNAI2 and GNAI3. May act as a scaffold integrating G protein and Ras/Raf MAPkinase signaling pathways. Inhibits platelet-derived growth factor (PDGF)-stimulated ERK1/ERK2 phosphorylation, a process depending on its interaction with HRAS and that is reversed by G(i) alpha subunit GNAI1. Acts as a positive modulator of microtubule polymerisation and spindle organization through a G(i)-alpha-dependent mechanism. Plays a role in cell division. Required for the nerve growth factor (NGF)-mediated neurite outgrowth. Involved in stress resistance. May be involved in visual memory processing capacity and hippocampal-based learning and memory.
Aliases: Highly similar to rap1/rap2 interacting protein antibody, OTTHUMP00000223586 antibody, OTTHUMP00000223587 antibody, Regulation of G protein signaling 14 antibody, Regulator of G protein signaling 14 antibody, Regulator of G protein signalling 14 antibody, Regulator of G-protein signaling 14 antibody, RGS 14 antibody, RGS14 antibody, RGS14_HUMAN antibody
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UniProt
- O43566
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
抗原
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