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FLT3 抗体 (AA 727-993)

FLT3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7167496
发货至: 中国
  • 抗原 See all FLT3 抗体
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    抗原表位
    • 19
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    AA 727-993
    适用
    • 129
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    宿主
    • 124
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    克隆类型
    • 125
    • 19
    多克隆
    标记
    • 70
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    This FLT3 antibody is un-conjugated
    应用范围
    • 108
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    Western Blotting (WB), ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Receptor-type tyrosine-protein kinase FLT3 protein (727-993AA)
    亚型
    IgG
    Top Product
    Discover our top product FLT3 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    别名
    FLT3 (FLT3 产品)
    背景

    Background: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.

    Aliases: CD 135 antibody, CD135 antibody, CD135 antigen antibody, Fetal liver kinase 2 antibody, FL cytokine receptor antibody, Flk 2 antibody, Flk2 antibody, Flt 3 antibody, FLT-3 antibody, Flt3 antibody, FLT3_HUMAN antibody, FMS like tyrosine kinase 3 antibody, Fms related tyrosine kinase 3 antibody, Fms-like tyrosine kinase 3 antibody, Growth factor receptor tyrosine kinase type III antibody, Ly-72 antibody, OTTHUMP0000004234 antibody, Receptor type tyrosine protein kinase FLT3 antibody, Stem cell tyrosine kinase 1 antibody, Stk 1 antibody, STK-1 antibody, Stk1 antibody, Tyrosine protein kinase receptor FLT3 antibody, Tyrosine-protein kinase receptor FLT3 antibody

    UniProt
    P36888
    途径
    RTK signaling
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