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RAB11A 抗体 (AA 2-213) (FITC)

This anti-RAB11A antibody is a 兔 多克隆 antibody detecting RAB11A in . Suitable for 人.
产品编号 ABIN7167223
发货至: 中国

Quick Overview for RAB11A 抗体 (AA 2-213) (FITC) (ABIN7167223)

抗原

See all RAB11A 抗体
RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))

适用

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宿主

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克隆类型

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多克隆

标记

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This RAB11A antibody is conjugated to FITC

应用范围

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  • 抗原表位

    • 10
    • 7
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    AA 2-213

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Ras-related protein Rab-11A protein (2-213AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))

    别名

    RAB11A

    背景

    Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B participates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells. Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane. Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes. May also play a role in melanosome transport and release from melanocytes.

    Aliases: MGC1490 antibody, Rab 11 antibody, Rab 11A antibody, RAB 11A, member oncogene family antibody, Rab-11 antibody, RAB11 A antibody, RAB11 antibody, Rab11a antibody, RAB11A member RAS oncogene family antibody, Ras related protein Rab 11A antibody, Ras related protein Rab11A antibody, Ras-related protein Rab-11A antibody, RB11A_HUMAN antibody, YL 8 antibody, YL8 antibody

    UniProt

    P62491

    途径

    Regulation of Cell Size, Thromboxane A2 Receptor Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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