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RAB11A 抗体

RAB11A 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 6C8 unconjugated
产品编号 ABIN4913381
发货至: 中国
  • 抗原 See all RAB11A 抗体
    RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))
    适用
    • 49
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    • 7
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    • 7
    • 7
    • 6
    • 6
    • 6
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    • 5
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    人, 小鼠, 大鼠
    宿主
    • 41
    • 5
    • 5
    小鼠
    克隆类型
    • 47
    • 4
    单克隆
    标记
    • 30
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
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    This RAB11A antibody is un-conjugated
    应用范围
    • 38
    • 25
    • 10
    • 8
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein G.
    免疫原
    This RAB11A antibody is generated from a mouse immunized with a purified recombinant protein of human RAB11A.
    克隆位点
    6C8
    亚型
    IgG1
    Top Product
    Discover our top product RAB11A Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))
    别名
    RAB11A (RAB11A 产品)
    别名
    rab11 antibody, RAB11A antibody, wu:fi15h09 antibody, zgc:103679 antibody, yl8 antibody, Rab11a antibody, rab11A antibody, DDBDRAFT_0190819 antibody, DDBDRAFT_0191190 antibody, DDB_0190819 antibody, DDB_0191190 antibody, YL8 antibody, RAB11 antibody, RAB11A, member RAS oncogene family S homeolog antibody, RAB11A, member RAS oncogene family antibody, RAB11a, member RAS oncogene family antibody, Rab11 GTPase antibody, rab11A protein antibody, Rab11a, GTPase antibody, Rab GTPase antibody, rab11A, RAB family GTPase antibody, rab11a.S antibody, RAB11A antibody, rab11a antibody, Rab11a antibody, rab11A antibody
    背景

    Synonyms: YL8, Ras-related protein Rab-11A, Rab-11, RAB11A, RAB11

    Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B participates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells. Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane. Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes. May also play a role in melanosome transport and release from melanocytes.

    基因ID
    8766
    UniProt
    P62491
    途径
    Regulation of Cell Size, Thromboxane A2 Receptor Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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