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RRAGA 抗体 (AA 1-247)

This 兔 多克隆 anti-RRAGA antibody specifically detects RRAGA in ELISA, IHC 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7167205
发货至: 中国
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Quick Overview for RRAGA 抗体 (AA 1-247) (ABIN7167205)

抗原

See all RRAGA 抗体
RRAGA (Ras-Related GTP Binding A (RRAGA))

适用

  • 27
  • 11
  • 11
  • 1

宿主

  • 27

克隆类型

  • 26
  • 1
多克隆

标记

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  • 4
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  • 3
  • 1
  • 1
  • 1
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  • 1
This RRAGA antibody is un-conjugated

应用范围

  • 15
  • 14
  • 11
  • 3
  • 3
  • 2
  • 1
ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 5
    • 2
    • 2
    • 1
    • 1
    AA 1-247

    原理

    RRAGA Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Ras-related GTP-binding protein A protein (1-247AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    RRAGA (Ras-Related GTP Binding A (RRAGA))

    别名

    RRAGA

    背景

    Background: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

    Aliases: Adenovirus E3 14.7 kDa-interacting protein 1 antibody, FIP-1 antibody, Rag A antibody, RagA antibody, Ras-related GTP-binding protein A antibody, RRAGA antibody, RRAGA_HUMAN antibody

    UniProt

    Q7L523
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