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RSAD2 抗体 (AA 42-361)

This anti-RSAD2 antibody is a 兔 多克隆 antibody detecting RSAD2 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7167058
发货至: 中国

Quick Overview for RSAD2 抗体 (AA 42-361) (ABIN7167058)

抗原

See all RSAD2 抗体
RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))

适用

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宿主

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克隆类型

  • 42
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多克隆

标记

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This RSAD2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 42-361

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Radical S-adenosyl methionine domain-containing protein 2 protein (42-361AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))

    别名

    RSAD2

    背景

    Background: Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV), hepatitis C virus (HCV), west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV), and human immunodeficiency virus (HIV-1). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphospate synthase (FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63\\\'-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.

    Aliases: 2510004L01Rik antibody, cig 33 antibody, CIG 5 antibody, cig-33 antibody, CIG-5 antibody, CIG33 antibody, CIG5 antibody, Cytomegalovirus induced gene 5 protein antibody, Cytomegalovirus-induced gene 5 protein antibody, endoplasmic reticulum-associated antibody, interferon-inducible antibody, Radical S adenosyl methionine domain containing 2 antibody, Radical S-adenosyl methionine domain-containing protein 2 antibody, RSAD 2 antibody, Rsad2 antibody, RSAD2_HUMAN antibody, RSDA-2 antibody, VIG 1 antibody, vig1 antibody, Viperin antibody, Virus inhibitory protein antibody, virus inhibitory protein endoplasmic reticulum associated interferon inducible antibody

    UniProt

    Q8WXG1

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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