SBNO2 抗体 (AA 6-146) (Biotin)
Quick Overview for SBNO2 抗体 (AA 6-146) (Biotin) (ABIN7166167)
抗原
See all SBNO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-146
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Protein strawberry notch homolog 2 protein (6-146AA)
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亚型
- IgG
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anti-Strawberry Notch Homolog 2 (SBNO2) (AA 6-146) antibody
SBNO2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SBNO2 (Strawberry Notch Homolog 2 (SBNO2))
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别名
- SBNO2
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背景
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Background: Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis, required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation (By similarity). Involved in the transcriptional corepression of NF-kappaB in macrophages (PubMed:18025162). Plays a role as a regulator in the proinflammatory cascade (PubMed:18025162).
Aliases: SBNO2 antibody, KIAA0963Protein strawberry notch homolog 2 antibody
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UniProt
- Q9Y2G9
抗原
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