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- 抗原 See all SBNO2 抗体
- SBNO2 (Strawberry Notch Homolog 2 (SBNO2))
- 抗原表位
- AA 6-146
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SBNO2 antibody is un-conjugated
- 应用范围
- ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Protein strawberry notch homolog 2 protein (6-146AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IF:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SBNO2 (Strawberry Notch Homolog 2 (SBNO2))
- 别名
- SBNO2 (SBNO2 产品)
- 别名
- KIAA0963 antibody, SNO antibody, STNO antibody, BC019206 antibody, F730040C21 antibody, Sno antibody, Stno antibody, strawberry notch homolog 2 antibody, strawberry notch homolog 2 (Drosophila) antibody, SBNO2 antibody, Sbno2 antibody
- 背景
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Background: Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis, required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation (By similarity). Involved in the transcriptional corepression of NF-kappaB in macrophages (PubMed:18025162). Plays a role as a regulator in the proinflammatory cascade (PubMed:18025162).
Aliases: SBNO2 antibody, KIAA0963Protein strawberry notch homolog 2 antibody
- UniProt
- Q9Y2G9
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