POGLUT1 抗体 (AA 132-392)
Quick Overview for POGLUT1 抗体 (AA 132-392) (ABIN7165879)
抗原
See all POGLUT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 132-392
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Protein O-glucosyltransferase 1 protein (132-392AA)
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亚型
- IgG
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anti-Protein O-Glucosyltransferase 1 (POGLUT1) (AA 160-280) antibody
POGLUT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein O-Glucosyltransferase 1 (POGLUT1) (AA 201-300) antibodyPOGLUT1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))
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别名
- POGLUT1
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背景
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Background: Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C (PubMed:21081508, PubMed:21490058, PubMed:21949356, PubMed:27807076). Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2 (PubMed:21081508, PubMed:21490058, PubMed:21949356, PubMed:27807076). Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development (PubMed:27807076). Notch glucosylation does not affect Notch ligand binding (PubMed:21490058). Required during early development to promote gastrulation: acts by mediating O-glucosylation of CRB2, which is required for CRB2 localization to the cell membrane (By similarity).
Aliases: C3orf9 antibody, CAP10 like 46 kDa protein antibody, CAP10 like protein, 46 kDa antibody, CAP10-like 46 kDa protein antibody, CLP46 antibody, hCLP46 antibody, hRumi antibody, KDELC family like 1 antibody, KDELCL1 antibody, KTEL (Lys Tyr Glu Leu) containing 1 antibody, KTEL motif containing protein 1 antibody, KTEL motif-containing protein 1 antibody, KTEL1 antibody, KTELC1 antibody, MDS010 antibody, MDSRP antibody, Myelodysplastic syndromes relative protein antibody, O-glucosyltransferase rumi homolog antibody, PGLT1_HUMAN antibody, Poglut1 antibody, protein O glucosyltransferase 1 antibody, Protein O-glucosyltransferase 1 antibody, Protein O-xylosyltransferase antibody, Rumi antibody, x 010 protein antibody
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UniProt
- Q8NBL1
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途径
- Notch Signaling
抗原
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