PQBP1 抗体 (AA 2-265) (FITC)
Quick Overview for PQBP1 抗体 (AA 2-265) (FITC) (ABIN7163842)
抗原
See all PQBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-265
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Polyglutamine-binding protein 1 protein (2-265AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
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别名
- PQBP1
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背景
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Background: Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species (PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.
Aliases: 38 kDa nuclear protein containing a WW domain antibody, Mental retardation, X linked 55 antibody, MRX55 antibody, MRXS3 antibody, MRXS8 antibody, Npw38 antibody, Nuclear protein containing WW domain 38 kD antibody, OTTHUMP00000025808 antibody, Polyglutamine binding protein 1 antibody, Polyglutamine tract binding protein 1 antibody, Polyglutamine tract-binding protein 1 antibody, Polyglutamine-binding protein 1 antibody, PQBP 1 antibody, PQBP-1 antibody, PQBP1 antibody, PQBP1_HUMAN antibody, RENS1 antibody, SHS antibody, Sutherland Haan X linked mental retardation syndrome antibody
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UniProt
- O60828
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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