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PKD1 抗体 (AA 615-753) (Biotin)

The Biotin-conjugated 兔 多克隆 anti-PKD1 antibody (ABIN7163833) specifically detects PKD1 in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7163833
发货至: 中国
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Quick Overview for PKD1 抗体 (AA 615-753) (Biotin) (ABIN7163833)

抗原

See all PKD1 抗体
PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

适用

  • 42
  • 11
  • 8

宿主

  • 40
  • 3
  • 1

克隆类型

  • 43
  • 1
多克隆

标记

  • 20
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PKD1 antibody is conjugated to Biotin

应用范围

  • 32
  • 15
  • 14
  • 14
  • 14
  • 12
  • 6
  • 5
  • 4
  • 3
  • 3
ELISA
  • 抗原表位

    • 16
    • 9
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 615-753

    原理

    PKD1 Antibody, Biotin conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Polycystin-1 protein (615-753AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

    别名

    PKD1

    背景

    Background: Involved in renal tubulogenesis (PubMed:12482949). Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium (By similarity). Acts as a regulator of cilium length, together with PKD2 (By similarity). The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling (By similarity). The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling (By similarity). May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate interactions.

    Aliases: Autosomal dominant polycystic kidney disease 1 protein antibody, Autosomal dominant polycystic kidney disease protein 1 antibody, nPKC-D1 antibody, nPKC-mu antibody, OTTHUMP00000208669 antibody, OTTHUMP00000208670 antibody, PBP antibody, Pc-1 antibody, PKD antibody, Pkd1 antibody, PKD1_HUMAN antibody, Polycystic Kidney Disease 1 antibody, polycystic kidney disease-associated protein antibody, Polycystin 1 Precursor antibody, Polycystin-1 antibody, Protein kinase C mu type antibody, Protein kinase D antibody, Serine/threonine-protein kinase D1 antibody, transient receptor potential cation channel, subfamily P, member 1 antibody, TRPP1 antibody

    UniProt

    P98161

    途径

    Myometrial Relaxation and Contraction, Maintenance of Protein Location
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