PKD1 抗体 (AA 615-753)
Quick Overview for PKD1 抗体 (AA 615-753) (ABIN7163832)
抗原
See all PKD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 615-753
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Polycystin-1 protein (615-753AA)
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亚型
- IgG
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anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (AA 651-876) antibody
PKD1 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (AA 131-230) antibodyPKD1 适用: 人, 小鼠 ELISA, WB, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (AA 349-612) antibodyPKD1 适用: 小鼠 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (pSer910) antibodyPKD1 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (pSer205) antibodyPKD1 适用: 人, 小鼠, 大鼠 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (Thr266), (Thr312) antibodyPKD1 适用: 人, 小鼠, 大鼠 IHC, ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))
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别名
- PKD1
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背景
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Background: Involved in renal tubulogenesis (PubMed:12482949). Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium (By similarity). Acts as a regulator of cilium length, together with PKD2 (By similarity). The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling (By similarity). The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling (By similarity). May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate interactions.
Aliases: Autosomal dominant polycystic kidney disease 1 protein antibody, Autosomal dominant polycystic kidney disease protein 1 antibody, nPKC-D1 antibody, nPKC-mu antibody, OTTHUMP00000208669 antibody, OTTHUMP00000208670 antibody, PBP antibody, Pc-1 antibody, PKD antibody, Pkd1 antibody, PKD1_HUMAN antibody, Polycystic Kidney Disease 1 antibody, polycystic kidney disease-associated protein antibody, Polycystin 1 Precursor antibody, Polycystin-1 antibody, Protein kinase C mu type antibody, Protein kinase D antibody, Serine/threonine-protein kinase D1 antibody, transient receptor potential cation channel, subfamily P, member 1 antibody, TRPP1 antibody
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UniProt
- P98161
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途径
- Myometrial Relaxation and Contraction, Maintenance of Protein Location
抗原
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