Poliovirus Receptor 抗体 (AA 220-345)
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Quick Overview for Poliovirus Receptor 抗体 (AA 220-345) (ABIN7163737)
抗原
See all Poliovirus Receptor (PVR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 220-345
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原理
- PVR Antibody
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交叉反应
- 小鼠
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Poliovirus receptor protein (220-345AA)
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亚型
- IgG
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anti-Poliovirus Receptor (PVR) (AA 21-343) antibody
PVR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6D2D6 unconjugated
anti-Poliovirus Receptor (PVR) (AA 22-255) antibodyPVR 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) antibodyPVR 适用: 小鼠 ELISA, FACS 宿主: 兔 Chimeric 3F1 unconjugated Recombinant Antibody
anti-Poliovirus Receptor (PVR) (AA 1-417) antibodyPVR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (AA 56-309) antibodyPVR 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) antibodyKD Validated PVR 适用: 人 WB 宿主: 兔 Monoclonal 23GB2575 unconjugated Recombinant Antibody
anti-Poliovirus Receptor (PVR) (Internal Region) antibodyPVR 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (AA 21-343) antibodyPVR 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM146 unconjugated
anti-Poliovirus Receptor (PVR) (AA 220-345) antibodyPVR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) antibodyPVR 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Poliovirus Receptor (PVR)
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别名
- PVR
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背景
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Background: Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration. Serves as a receptor for poliovirus attachment to target cells. May play a role in axonal transport of poliovirus, by targeting virion-PVR-containing endocytic vesicles to the microtubular network through interaction with DYNLT1. This interaction would drive the virus-containing vesicle to the axonal retrograde transport.2 Publications
Aliases: CD155 antibody, CD155 antigen antibody, FLJ25946 antibody, HVED antibody, mE4 antibody, NECL 5 antibody, Necl-5 antibody, Necl5 antibody, Nectin like 5 antibody, Nectin like protein 5 antibody, Nectin-like protein 5 antibody, Ortholog of mouse Tage4 antibody, Poliovirus receptor antibody, PVR antibody, PVR_HUMAN antibody, PVS antibody, Taa1 antibody, Tage 4 antibody, TAGE4 antibody
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UniProt
- P15151
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
抗原
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