PITX3 抗体 (AA 10-200)
Quick Overview for PITX3 抗体 (AA 10-200) (ABIN7163469)
抗原
See all PITX3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 10-200
-
交叉反应
- 人, 小鼠
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human Pituitary homeobox 3 protein (10-200AA)
-
亚型
- IgG
-
-
anti-Pituitary Homeobox 3 (PITX3) (AA 231-302) antibody
PITX3 适用: 小鼠, 大鼠, Cow WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) antibodyPITX3 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) (N-Term) antibodyPITX3 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) (N-Term) antibodyPITX3 适用: 人, 小鼠 IHC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) (N-Term) antibodyPITX3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 绵羊, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) (Internal Region) antibodyVerified PITX3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) (AA 144-193) antibodyPITX3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 绵羊, 豚鼠, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) (AA 1-70) antibodyPITX3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) antibodyPITX3 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
-
-
应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- PITX3 (Pituitary Homeobox 3 (PITX3))
-
别名
- PITX3
-
背景
-
Background: Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. In addition to its importance during development, it also has roles in the long-term survival and maintenance of the mdDA neurons. Activates NR4A2/NURR1-mediated transcription of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. Acts by decreasing the interaction of NR4A2/NURR1 with the corepressor NCOR2/SMRT which acts through histone deacetylases (HDACs) to keep promoters of NR4A2/NURR1 target genes in a repressed deacetylated state. Essential for the normal lens development and differentiation. Plays a critical role in the maintenance of mitotic activity of lens epithelial cells, fiber cell differentiation and in the control of the temporal and spatial activation of fiber cell-specific crystallins. Positively regulates FOXE3 expression and negatively regulates PROX1 in the anterior lens epithelium, preventing activation of CDKN1B/P27Kip1 and CDKN1C/P57Kip2 and thus maintains lens epithelial cells in cell cycle (By similarity).
Aliases: Homeobox protein PITX 3 antibody, Homeobox protein PITX3 antibody, MGC12766 antibody, Paired like homeodomain transcription factor 3 antibody, Paired-like homeodomain transcription factor 3 antibody, Pituitary homeobox 3 antibody, PITX 3 antibody, Pitx3 antibody, PITX3_HUMAN antibody, PTX 3 antibody, PTX3 antibody
-
UniProt
- O75364
抗原
-
