PIK3R6 抗体 (Regulatory Subunit 6) (FITC)
Quick Overview for PIK3R6 抗体 (Regulatory Subunit 6) (FITC) (ABIN7163301)
抗原
See all PIK3R6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 566-667, Regulatory Subunit 6
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Phosphoinositide 3-kinase regulatory subunit 6 protein (566-667AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))
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别名
- PIK3R6
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背景
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Background: Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis, signaling seems to involve RRAS.
Aliases: C17orf38 antibody, Chromosome 17 open reading frame 38 antibody, HsT41028 antibody, p84 PI3K adapter protein antibody, p84 PIKAP antibody, p87 phosphoinositide 3-kinase gamma (PI3Kg) adapter protein antibody, p87 PI3K adapter protein antibody, p87PIKAP antibody, Phosphatidylinositol 3-kinase, regulatory subunit 6 antibody, Phosphoinositide 3-kinase gamma adapter protein of 87 kDa antibody, Phosphoinositide 3-kinase regulatory subunit 6 antibody, PI3Kgamma adapter protein of 87 kDa antibody, PI3R6_HUMAN antibody, PIK3R6 antibody
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UniProt
- Q5UE93
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途径
- PI3K-Akt Signaling, Inositol Metabolic Process
抗原
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