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PIK3R1 抗体 (Regulatory Subunit A)

PI3K p85a 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7163163
发货至: 中国
  • 抗原 See all PIK3R1 (PI3K p85a) 抗体
    PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
    抗原表位
    • 19
    • 15
    • 15
    • 10
    • 9
    • 9
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    AA 160-376, Regulatory Subunit A
    适用
    • 129
    • 89
    • 67
    • 17
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    • 4
    • 3
    • 2
    • 2
    • 2
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    宿主
    • 110
    • 30
    克隆类型
    • 98
    • 42
    多克隆
    标记
    • 75
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    This PIK3R1 antibody is un-conjugated
    应用范围
    • 112
    • 55
    • 40
    • 28
    • 21
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    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Phosphatidylinositol 3-kinase regulatory subunit alpha protein (160-376AA)
    亚型
    IgG
    Top Product
    Discover our top product PI3K p85a Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
    别名
    PIK3R1 (PI3K p85a 产品)
    背景

    Background: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling (PubMed:17626883, PubMed:19805105, PubMed:7518429). Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress-and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (PubMed:20348923).

    Aliases: GRB1 antibody, p85 alpha antibody, p85 antibody, P85A_HUMAN antibody, Phosphatidylinositol 3 kinase associated p 85 alpha antibody, Phosphatidylinositol 3 kinase regulatory 1 antibody, Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 1 (p85 alpha) antibody, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha antibody, Phosphatidylinositol 3-kinase regulatory subunit alpha antibody, Phosphoinositide 3 kinase, regulatory subunit 1 (alpha) antibody, PI3 kinase p85 antibody, PI3 kinase p85 subunit alpha antibody, PI3-kinase regulatory subunit alpha antibody, PI3-kinase subunit p85-alpha antibody, PI3K antibody, PI3K p85 antibody, PI3K regulatory subunit alpha antibody, Pik3r1 antibody, PtdIns 3 kinase p85 alpha antibody, PtdIns-3-kinase regulatory subunit alpha antibody, PtdIns-3-kinase regulatory subunit p85-alpha antibody

    UniProt
    P27986
    途径
    TCR Signaling, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effect
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