PPARA 抗体 (AA 1-237)
Quick Overview for PPARA 抗体 (AA 1-237) (ABIN7163009)
抗原
See all PPARA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-237
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交叉反应
- 人
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纯化方法
- >95%, Antigen Affinity purified & Affinity purified
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免疫原
- Recombinant Human Peroxisome proliferator-activated receptor alpha protein (1-237AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:1000-1:5000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
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别名
- PPARA
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背景
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Background: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Aliases: hPPAR antibody, MGC2237 antibody, MGC2452 antibody, NR1C1 antibody, Nuclear receptor subfamily 1 group C member 1 antibody, OTTHUMP00000197740 antibody, OTTHUMP00000197741 antibody, Peroxisome proliferative activated receptor alpha antibody, Peroxisome proliferator activated receptor alpha antibody, Peroxisome proliferator-activated receptor alpha antibody, PPAR antibody, PPAR-alpha antibody, ppara antibody, PPARA_HUMAN antibody, PPARalpha antibody
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UniProt
- Q07869
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
抗原
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