PASK 抗体 (AA 482-602) (Biotin)
Quick Overview for PASK 抗体 (AA 482-602) (Biotin) (ABIN7162685)
抗原
See all PASK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 482-602
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human PAS domain-containing serine/threonine-protein kinase protein (482-602AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PASK (PAS Domain Containing Serine/threonine Kinase (PASK))
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别名
- PASK
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背景
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Background: Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells, however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate to respiratory regulation.
Aliases: DKFZP434O051 antibody, DKFZp686P2031 antibody, hPASK antibody, KIAA0135 antibody, MGC93882 antibody, mKIAA0135 antibody, PAS domain containing serine/threonine kinase antibody, PAS domain containing serine/threonine protein kinase antibody, PAS domain-containing serine/threonine-protein kinase antibody, PAS kinase antibody, PAS serine/threonine kinase antibody, PAS-kinase antibody, Pask antibody, PASK_HUMAN antibody, PASKIN antibody, STK 37 antibody, STK37 antibody
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UniProt
- Q96RG2
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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