PAN2 抗体 (AA 628-908) (Biotin)
Quick Overview for PAN2 抗体 (AA 628-908) (Biotin) (ABIN7162472)
抗原
See all PAN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 628-908
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human PAB-dependent poly(A)-specific ribonuclease subunit PAN2 protein (628-908AA)
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亚型
- IgG
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anti-PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2) (AA 628-908) antibody
PAN2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2) (AA 1099-1198) antibodyPAN2 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 6A7 unconjugated
anti-PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2) (AA 700-1000) antibodyPAN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PAN2 (PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2))
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别名
- PAN2
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背景
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Background: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein (PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3\\\'-5\\\' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5\\\'-3\\\' exonucleolytic degradation by XRN1.
Aliases: hPan2 antibody, Inactive ubiquitin carboxyl terminal hydrolase 52 antibody, Inactive ubiquitin carboxyl-terminal hydrolase 52 antibody, KIAA0710 antibody, PAB dependent poly(A) specific ribonuclease subunit 2 antibody, PAB-dependent poly(A)-specific ribonuclease subunit 2 antibody, PABP dependent poly(A) nuclease 2 antibody, PAN 2 antibody, PAN2 antibody, PAN2 homolog PABP1 dependent poly A specific ribonuclease subunit antibody, PAN2 poly(A) specific ribonuclease subunit homolog antibody, PAN2 polyA specific ribonuclease subunit homolog antibody, PAN2_HUMAN antibody, Ubiquitin specific peptidase 52 antibody, Ubiquitin specific protease 52 antibody, USP 52 antibody, USP52 antibody
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UniProt
- Q504Q3
抗原
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