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PAN2 抗体 (AA 628-908)

PAN2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7162471
发货至: 中国
  • 抗原 See all PAN2 抗体
    PAN2 (PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2))
    抗原表位
    • 10
    • 8
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 628-908
    适用
    • 25
    • 2
    • 1
    宿主
    • 24
    • 1
    克隆类型
    • 24
    • 1
    多克隆
    标记
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    This PAN2 antibody is un-conjugated
    应用范围
    • 21
    • 17
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human PAB-dependent poly(A)-specific ribonuclease subunit PAN2 protein (628-908AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PAN2 (PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2))
    别名
    PAN2 (PAN2 产品)
    别名
    USP52 antibody, 1200014O24Rik antibody, AI047843 antibody, AW742773 antibody, Usp52 antibody, mKIAA0710 antibody, PAN2 antibody, pan2 antibody, PAN2 poly(A) specific ribonuclease subunit antibody, PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) antibody, PAN2 poly(A) specific ribonuclease subunit S homeolog antibody, PAN2 antibody, Pan2 antibody, pan2.S antibody
    背景

    Background: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein (PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3\\\'-5\\\' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5\\\'-3\\\' exonucleolytic degradation by XRN1.

    Aliases: hPan2 antibody, Inactive ubiquitin carboxyl terminal hydrolase 52 antibody, Inactive ubiquitin carboxyl-terminal hydrolase 52 antibody, KIAA0710 antibody, PAB dependent poly(A) specific ribonuclease subunit 2 antibody, PAB-dependent poly(A)-specific ribonuclease subunit 2 antibody, PABP dependent poly(A) nuclease 2 antibody, PAN 2 antibody, PAN2 antibody, PAN2 homolog PABP1 dependent poly A specific ribonuclease subunit antibody, PAN2 poly(A) specific ribonuclease subunit homolog antibody, PAN2 polyA specific ribonuclease subunit homolog antibody, PAN2_HUMAN antibody, Ubiquitin specific peptidase 52 antibody, Ubiquitin specific protease 52 antibody, USP 52 antibody, USP52 antibody

    UniProt
    Q504Q3
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