OSBP 抗体 (AA 628-802)
Quick Overview for OSBP 抗体 (AA 628-802) (ABIN7162395)
抗原
See all OSBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 628-802
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Oxysterol-binding protein 1 protein (628-802AA)
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亚型
- IgG
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anti-Oxysterol Binding Protein (OSBP) (AA 324-407) antibody
OSBP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5A3 unconjugated
anti-Oxysterol Binding Protein (OSBP) (Internal Region) antibodyOSBP 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (AA 508-807) antibodyOSBP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (AA 700-749) antibodyOSBP 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (C-Term) antibodyVerified OSBP 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (AA 546-807) antibodyOSBP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- OSBP (Oxysterol Binding Protein (OSBP))
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别名
- OSBP
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背景
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Background: Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum (PubMed:24209621). Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol (PubMed:15746430, PubMed:17428193). Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly (PubMed:15746430). Regulates cholesterol efflux by decreasing ABCA1 stability (PubMed:18450749).
Aliases: OSBP 1 antibody, OSBP antibody, OSBP1_HUMAN antibody, Oxysterol binding protein 1 antibody, Oxysterol-binding protein 1 antibody
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UniProt
- P22059
抗原
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