OTUD7B 抗体 (AA 235-347) (Biotin)
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北京 101111
Quick Overview for OTUD7B 抗体 (AA 235-347) (Biotin) (ABIN7162339)
抗原
See all OTUD7B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 235-347
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原理
- OTUD7B Antibody, Biotin conjugated
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human OTU domain-containing protein 7B protein (235-347AA)
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亚型
- IgG
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anti-OTU Domain Containing 7B (OTUD7B) (AA 759-858) antibody
OTUD7B 适用: 人 ELISA, WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 2B4 unconjugated
anti-OTU Domain Containing 7B (OTUD7B) (AA 235-347) antibodyOTUD7B 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 7B (OTUD7B) (C-Term) antibodyOTUD7B 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 7B (OTUD7B) (Middle Region) antibodyOTUD7B 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 7B (OTUD7B) (AA 1-427) antibodyOTUD7B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-OTU Domain Containing 7B (OTUD7B) (AA 559-608) antibodyOTUD7B 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 7B (OTUD7B) (AA 612-661) antibodyOTUD7B 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, Pig, 兔, Bat, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 7B (OTUD7B) (AA 757-784), (C-Term) antibodyOTUD7B 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- OTUD7B (OTU Domain Containing 7B (OTUD7B))
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别名
- OTUD7B
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背景
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Background: Negative regulator of the non-canonical NF-kappa-B pathway that acts by mediating deubiquitination of TRAF3, an inhibitor of the NF-kappa-B pathway, thereby acting as a negative regulator of B-cell responses. In response to non-canonical NF-kappa-B stimuli, deubiquitinates \'Lys-48\'-linked polyubiquitin chains of TRAF3, preventing TRAF3 proteolysis and over-activation of non-canonical NF-kappa-B. Negatively regulates mucosal immunity against infections (By similarity). Deubiquitinates ZAP70, and thereby regulates T cell receptor (TCR) signaling that leads to the activation of NF-kappa-B (PubMed:26903241). Plays a role in T cell homeostasis and is required for normal T cell responses, including production of IFNG and IL2 (By similarity). Mediates deubiquitination of EGFR (PubMed:22179831). Has deubiquitinating activity toward \'Lys-11\', \'Lys-48\' and \'Lys-63\'-linked polyubiquitin chains (PubMed:27732584). Has a much higher catalytic rate with \'Lys-11\'-linked polyubiquitin chains (in vitro), however the physiological significance of these data are unsure (PubMed:27732584). Hydrolyzes both linear and branched forms of polyubiquitin.
Aliases: Cellular zinc finger anti NF kappa B protein antibody, Cellular zinc finger anti-NF-kappa-B protein antibody, CEZANNE antibody, HGNC:16683 antibody, OTU domain containing protein 7B antibody, OTU domain-containing protein 7B antibody, OTU7B_HUMAN antibody, OTUD7B antibody, ZA20D1 antibody, Zinc finger A20 domain containing protein 1 antibody, Zinc finger A20 domain-containing protein 1 antibody, Zinc finger protein Cezanne antibody
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UniProt
- Q6GQQ9
抗原
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