OAZ1 抗体 (AA 1-68)
Quick Overview for OAZ1 抗体 (AA 1-68) (ABIN7162292)
抗原
See all OAZ1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-68
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Ornithine decarboxylase antizyme 1 protein (1-68AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))
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别名
- OAZ1
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背景
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Background: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake by binding to and targeting ODC1 for degradation (PubMed:17900240). Stabilizes AZIN2 by interfering with its ubiquitination. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol.
Aliases: Antizyme 1 antibody, Antizyme antibody, AZI antibody, MGC138338 antibody, OAZ 1 antibody, OAZ antibody, OAZ1 antibody, OAZ1_HUMAN antibody, ODC Az antibody, ODC-Az antibody, Ornithine decarboxylase antizyme 1 antibody, Ornithine decarboxylase antizyme antibody
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UniProt
- P54368
抗原
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