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TSC1 抗体 (pSer505) (FITC)

TSC1 适用: 人, 小鼠, 绵羊 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal FITC
产品编号 ABIN711978
发货至: 中国
  • 抗原 See all TSC1 抗体
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    抗原表位
    • 23
    • 16
    • 16
    • 16
    • 15
    • 15
    • 13
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer505
    适用
    • 187
    • 138
    • 53
    • 24
    • 17
    • 2
    • 1
    • 1
    人, 小鼠, 绵羊
    宿主
    • 301
    • 16
    • 1
    • 1
    克隆类型
    • 303
    • 16
    多克隆
    标记
    • 114
    • 36
    • 36
    • 36
    • 32
    • 32
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This TSC1 antibody is conjugated to FITC
    应用范围
    • 230
    • 208
    • 91
    • 28
    • 25
    • 25
    • 16
    • 14
    • 9
    • 7
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 绵羊
    预测反应
    Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human TSC1 around the phosphorylation site of Ser505 [FD(p-S)PF]
    亚型
    IgG
    Top Product
    Discover our top product TSC1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    别名
    TSC1 (TSC1 产品)
    别名
    LAM antibody, TSC antibody, hamartin antibody, mKIAA0243 antibody, tsc1 antibody, wu:fc38b04 antibody, fa99f04 antibody, wu:fa99f04 antibody, zgc:63657 antibody, TSC complex subunit 1 antibody, tuberous sclerosis 1 antibody, TSC complex subunit 1b antibody, TSC complex subunit 1a antibody, TSC1 antibody, Tsc1 antibody, tsc1b antibody, tsc1 antibody, tsc1a antibody
    背景

    Synonyms: TSC1phospho S505, LAM, TSC1, Tuberous sclerosis 1 protein.

    Background: Hamartin, or TSC1, is a suspected tumor suppressor implicated in the disease tuberous sclerosis 1. It is a negative regulator of cell division controlling the transition from G0/G1 to S phase, and it seems to act through the phosphatidylinositol 3 kinase/Akt pathway. TSC1 interacts with tuberin m(TSC2), which is thought to be a GAP (GTPase Activating Protein) for the Rap1 and Rab5 small G Proteins. The Hamartin/Tuberin complex has been shown to inhibit mTor. Hamartin has also been shown to interact with ERM (Ezrin-Radixin-Moesin) proteins and with F-actin, suggesting a role for TSC proteins in modulation of cell adhesion and morphology.

    基因ID
    7248
    途径
    RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
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