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TSC1 抗体 (pSer505)

Name: TSC1 抗体 (pSer505)
SKU: ABIN711971
Availability: OutOfStock

This anti-TSC1 antibody is a 兔多克隆 antibody detecting TSC1 in ELISA, WB, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人, 小鼠和绵羊. This Primary Antibody has been cited in 1 publication.

ELISA

1 image

(1 reference)

产品编号 ABIN711971

发货至: 中国

Quick Overview for TSC1 抗体 (pSer505) (ABIN711971)

抗原

See all TSC1 抗体

TSC1 (Tuberous Sclerosis 1 (TSC1))

适用

人, 小鼠, 绵羊

宿主

兔

克隆类型

多克隆

标记

This TSC1 antibody is un-conjugated

应用范围

ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product TSC1 Primary Antibody

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pSer505

交叉反应

人, 小鼠, 绵羊

预测反应

Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic phosphopeptide derived from human TSC1 around the phosphorylation site of Ser505 [FD(p-S)PF]

亚型

IgG
anti-Tuberous Sclerosis 1 (TSC1) (AA 836-1164) antibody
TSC1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A2 unconjugated

anti-Tuberous Sclerosis 1 (TSC1) (AA 550-650) antibody
TSC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Tuberous Sclerosis 1 (TSC1) (C-Term) antibody
TSC1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tuberous Sclerosis 1 (TSC1) (AA 836-1164) antibody
TSC1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5A8 unconjugated

anti-Tuberous Sclerosis 1 (TSC1) antibody
TSC1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Tuberous Sclerosis 1 (TSC1) (AA 401-430) antibody
TSC1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Tuberous Sclerosis 1 (TSC1) (AA 101-344) antibody
TSC1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Tuberous Sclerosis 1 (TSC1) (AA 401-430) antibody
TSC1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB11648 unconjugated

anti-Tuberous Sclerosis 1 (TSC1) (AA 131-230) antibody
TSC1 适用: 绵羊 ELISA, WB 宿主: 兔 Polyclonal unconjugated

anti-Tuberous Sclerosis 1 (TSC1) (C-Term) antibody
Verified TSC1 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Cao, Wei, Liu, Wang, Wu, Xie, Capellini, Zhang, Zhao, Li, Zhong, Wang, Lu, Liu, Zhang, Du, Zhang, Du: "DNA methylation Landscape of body size variation in sheep." in: Scientific reports, Vol. 5, pp. 13950, (2016) (PubMed).
抗原

TSC1 (Tuberous Sclerosis 1 (TSC1))

别名

TSC1

背景

Synonyms: TSC1phospho S505, LAM, TSC1, Tuberous sclerosis 1 protein.
Background: Hamartin, or TSC1, is a suspected tumor suppressor implicated in the disease tuberous sclerosis 1. It is a negative regulator of cell division controlling the transition from G0/G1 to S phase, and it seems to act through the phosphatidylinositol 3 kinase/Akt pathway. TSC1 interacts with tuberin m(TSC2), which is thought to be a GAP (GTPase Activating Protein) for the Rap1 and Rab5 small G Proteins. The Hamartin/Tuberin complex has been shown to inhibit mTor. Hamartin has also been shown to interact with ERM (Ezrin-Radixin-Moesin) proteins and with F-actin, suggesting a role for TSC proteins in modulation of cell adhesion and morphology.

基因ID

7248

途径

RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation