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nectin-3 抗体 (AA 310-549)

This 兔 多克隆 antibody specifically detects nectin-3 in ELISA 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7161113
发货至: 中国
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Quick Overview for nectin-3 抗体 (AA 310-549) (ABIN7161113)

抗原

See all nectin-3 (NECTIN3) 抗体
nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

适用

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宿主

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克隆类型

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多克隆

标记

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This nectin-3 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 310-549

    原理

    NECTIN3 Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Nectin-3 protein (310-549AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

    别名

    NECTIN3

    背景

    Background: Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.

    Aliases: CD113 antibody, CDw113 antibody, DKFZP566B0846 antibody, FLJ90624 antibody, Nectin-3 antibody, Nectin3 antibody, Poliovirus receptor related 3 antibody, Poliovirus receptor related protein 3 antibody, Poliovirus receptor-like 3 antibody, Poliovirus receptor-related protein 3 antibody, PPR3 antibody, PRR3 antibody, Pvrl3 antibody, PVRL3_HUMAN antibody, PVRR3 antibody

    UniProt

    Q9NQS3

    途径

    Cell-Cell Junction Organization
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