nectin-3 抗体 (AA 310-549)
Quick Overview for nectin-3 抗体 (AA 310-549) (ABIN7161113)
抗原
See all nectin-3 (NECTIN3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 310-549
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Nectin-3 protein (310-549AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
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别名
- NECTIN3
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背景
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Background: Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
Aliases: CD113 antibody, CDw113 antibody, DKFZP566B0846 antibody, FLJ90624 antibody, Nectin-3 antibody, Nectin3 antibody, Poliovirus receptor related 3 antibody, Poliovirus receptor related protein 3 antibody, Poliovirus receptor-like 3 antibody, Poliovirus receptor-related protein 3 antibody, PPR3 antibody, PRR3 antibody, Pvrl3 antibody, PVRL3_HUMAN antibody, PVRR3 antibody
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UniProt
- Q9NQS3
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途径
- Cell-Cell Junction Organization
抗原
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