NADPH Oxidase 4 抗体 (AA 210-424)
Quick Overview for NADPH Oxidase 4 抗体 (AA 210-424) (ABIN7161010)
抗原
See all NADPH Oxidase 4 (NOX4) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 210-424
-
交叉反应
- 人
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human NADPH oxidase 4 protein (210-424AA)
-
亚型
- IgG
-
-
-
-
应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- NADPH Oxidase 4 (NOX4)
-
别名
- NOX4
-
背景
-
Background: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity.
Aliases: Kidney oxidase 1 antibody, Kidney oxidase-1 antibody, Kidney superoxide producing NADPH oxidase antibody, Kidney superoxide-producing NADPH oxidase antibody, KOX 1 antibody, KOX antibody, Kox-1 antibody, KOX1 antibody, NADPH antibody, NADPH oxidase 4 antibody, Nox4 antibody, NOX4_HUMAN antibody, Renal NAD(P)H oxidase antibody, Renal NAD(P)H-oxidase antibody, RENOX antibody
-
UniProt
- Q9NPH5
-
途径
- Carbohydrate Homeostasis, Smooth Muscle Cell Migration
抗原
-