NLRP1 抗体 (AA 589-655) (Biotin)
Quick Overview for NLRP1 抗体 (AA 589-655) (Biotin) (ABIN7160822)
抗原
See all NLRP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 589-655
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human NACHT, LRR and PYD domains-containing protein 10 protein (589-655AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
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别名
- NLRP1
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背景
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Background: Inhibits autoprocessing of CASP1, CASP1-dependent IL1B secretion, PYCARD aggregation and PYCARD-mediated apoptosis but not apoptosis induced by FAS or BID. Displays anti-inflammatory activity. Plays a role in adaptive immunity through control of dendritic cell-mediated transport of antigen to the lymph nodes from peripheral sites. Required for immunity against C.albicans infection. Involved in the innate immune response by contributing to proinflammatory cytokine release in response to invasive bacterial infection.
Aliases: CLR11.1 antibody, NACHT, leucine rich repeat and PYD containing 10 antibody, NACHT, LRR and PYD domains containing protein 10 antibody, NACHT, LRR and PYD domains-containing protein 10 antibody, NAL10_HUMAN antibody, NALP10 antibody, NLR family, pyrin domain containing 10 antibody, Nlrp10 antibody, NOD8 antibody, Nucleotide-binding oligomerization domain protein 8 antibody, Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10 antibody, PAN5 antibody, PYNOD antibody
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UniProt
- Q86W26
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途径
- Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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