MLF1 抗体 (AA 1-268)
Quick Overview for MLF1 抗体 (AA 1-268) (ABIN7160476)
抗原
See all MLF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-268
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交叉反应
- 人, 小鼠
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Myeloid leukemia factor 1 protein (1-268AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MLF1 (Myeloid Leukemia Factor 1 (MLF1))
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别名
- MLF1
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背景
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Background: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Aliases: Hls7 antibody, MLF1 antibody, MLF1_HUMAN antibody, Myelodysplasia myeloid leukemia factor 1 antibody, Myelodysplasia-myeloid leukemia factor 1 antibody, Myeloid leukemia factor 1 antibody, myeloid leukemia factor 1 variant 1 antibody, myeloid leukemia factor 1 variant 2 antibody, myeloid leukemia factor 1 variant 3 antibody
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UniProt
- P58340
抗原
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